Testosterone replacement therapy (TRT) is a medical treatment designed to restore testosterone levels in low testosterone (low T) men. By completing the body’s natural hormone production, it can help to improve symptoms such as fatigue, low libido, muscle loss, and mood changes.
How TRT works in the body
Testosterone is a key hormone responsible for muscle growth, bone density, energy levels and sexual health. When the levels fall due to aging, diseases or other factors, TRT helps to provide external testosterone to restore balance.
After induction, testosterone enters blood circulation and is associated with androgen receptors in tissues such as muscles, bones, and brain. This activates biological processes that regulate protein synthesis, the production of red blood cells and sexual desire.
How to get started with TRT
- Injections (intramuscular or subcutaneous) are the most common and economical method. Injections are given weekly or once every two weeks to maintain stable levels of testosterone.
- Gels and Creams – Applied daily to the skin, allowing testosterone to be absorbed gradually.
- Patches – Worn on the skin and replaced daily for steady hormone release.
- Pellet – Embedded under the skin and releases testosterone for several months.
- Oral capsules – a new method that avoids injections but can affect liver function.
Effects and Benefits of TRT
TRT can help improve:
- Energy levels and reduces fatigue.
- Muscle mass and bone density.
- Libido and sexual performance.
- Mood by reducing irritability and depression.
Monitoring and safety
Regular blood tests guarantee that the level of testosterone remains in a healthy range. Doctors also monitor the number of red blood cells, estrogen levels and prostate health to minimize the risks of TRT. Read here more about how TRT is done. If you want to know more about the benefits of TRT you can read that here.