Testosterone Replacement Therapy (TRT) comes in various forms, each with its own benefits and drawbacks. The best TRT option depends on factors such as lifestyle, convenience, medical conditions, and personal preference. Below, we explore the most common TRT methods and their advantages to help determine which may be the best choice for different individuals.

1. Testosterone Injections

Testosterone injections are one of the most widely used and effective TRT methods. They typically come in two forms:

  • Short-acting injections (Testosterone Propionate): Require frequent dosing, often every other day.
  • Long-acting injections (Testosterone Enanthate, Testosterone Cypionate): Administered every 1-2 weeks, providing a more stable hormone level.

Pros:

  • Cost-effective compared to other options.
  • Reliable and widely available.
  • Allows for precise dosage control.

Cons:

  • Requires injections, which some individuals may find uncomfortable.
  • Potential for fluctuations in testosterone levels between doses.

2. Testosterone Gels

Testosterone gels, such as AndroGel and Testim, are applied daily to the skin, allowing for a steady absorption of testosterone.

Pros:

  • Non-invasive and easy to use.
  • Provides consistent testosterone levels without major fluctuations.

Cons:

  • Risk of transference to others through skin contact.
  • Some individuals may experience skin irritation.
  • More expensive than injections.

3. Testosterone Patches

Transdermal testosterone patches, like Androderm, deliver a controlled dose of testosterone through the skin over 24 hours.

Pros:

  • Provides a steady release of testosterone.
  • Easy application, similar to gels.

Cons:

  • May cause skin irritation or allergic reactions.
  • Can be less effective if the patch doesn’t adhere properly.
  • Less commonly used due to comfort issues.

4. Testosterone Pellets

Testosterone pellets (Testopel) are small implants placed under the skin, usually in the hip or buttocks, that slowly release testosterone over 3-6 months.

Pros:

  • Long-lasting and convenient, eliminating the need for daily or weekly administration.
  • Provides consistent testosterone levels.

Cons:

  • Requires a minor surgical procedure for insertion and removal.
  • Higher initial cost.
  • Risk of pellet extrusion or infection.

5. Testosterone Oral Pills and Buccal Tablets

Testosterone pills and buccal tablets (placed against the gums) offer an alternative to injections and gels. However, oral testosterone is not widely recommended due to its impact on liver health.

Pros:

  • Convenient and easy to take.

Cons:

  • Some oral forms can cause liver toxicity.
  • Less effective absorption compared to injections or gels.

Boost Health Clinic can prescribe testosterone replacement therapy if you have low T. Learn here more about trt.